Overview of Tenofovir Disoproxil Fumarate
Tenofovir Disoproxil Fumarate is a medication used to treat HIV-1 infection and chronic HBV infection․ It is important to monitor patients closely after discontinuation and watch for side effects․ See full prescribing information for detailed guidance․
What is Tenofovir Disoproxil Fumarate?
Tenofovir Disoproxil Fumarate is an antiretroviral medication used in the treatment of HIV infection in adults, adolescents, and pediatric patients․ It is also utilized in the management of chronic HBV infection in both adult and pediatric populations․ This medication works by inhibiting viral replication of HIV-1 and HBV٫ thus helping to control the infections․ Tenofovir Disoproxil Fumarate is commonly prescribed in combination with other antiretroviral medications to form a comprehensive treatment regimen․ It is available in various formulations٫ including tablets and oral powder٫ with specific dosing instructions for each․ Prior to starting treatment with Tenofovir Disoproxil Fumarate٫ patients should undergo testing for HBV and HIV-1 infections and continue to be monitored regularly for kidney function and other relevant parameters during the course of therapy․ This medication plays a crucial role in the management of HIV and HBV infections٫ improving patient outcomes and quality of life․
Precautions
Patients should be monitored for exacerbations of hepatitis after discontinuing anti-HBV therapy, including Tenofovir Disoproxil Fumarate․ Additionally, severe side effects such as lactic acidosis, liver problems, and kidney issues may occur, requiring immediate medical attention․
Monitoring Hepatic Function
Tenofovir Disoproxil Fumarate, like many medications, can have an impact on hepatic function․ Patients should undergo regular monitoring for any changes in liver enzymes and function․ This precaution helps to detect any potential liver issues early on and allows for prompt intervention if necessary․
Side Effects and Allergic Reactions
When taking Tenofovir Disoproxil Fumarate, patients should be aware of potential side effects and allergic reactions․ It is crucial to seek immediate medical attention if any signs of allergic reactions such as hives, difficulty breathing, or swelling occur․ Additionally, patients should watch for symptoms of lactic acidosis, liver problems, kidney issues, or any unusual symptoms that may indicate life-threatening side effects, and promptly consult a healthcare provider if such symptoms arise․
Warnings
Patients treated with Tenofovir Disoproxil Fumarate should be closely monitored for severe acute exacerbations of hepatitis B virus, which can occur after discontinuing the medication․ It is crucial to maintain rigorous clinical and laboratory follow-up for at least several months post-discontinuation for appropriate management․
Exacerbation of Hepatitis after Discontinuation of Treatment
Patients using Tenofovir Disoproxil Fumarate should be aware of the risk of severe acute exacerbations of hepatitis B virus (HBV) following the discontinuation of anti-HBV therapy, including Tenofovir Disoproxil Fumarate․ Close monitoring of hepatic function, both clinically and through laboratory testing, is essential for at least several months post-discontinuation to promptly address any exacerbations of hepatitis․
Life-Threatening Side Effects
Tenofovir Disoproxil Fumarate can lead to severe, life-threatening side effects such as lactic acidosis, liver problems, and kidney issues․ Immediate medical attention is necessary if any signs of allergic reactions or these side effects, including unusual muscle pain, trouble breathing, stomach pain, vomiting, or irregular heartbeats, are experienced․